Single cell at Scale

Cell Atlasing

Amplify your atlasing efforts with more samples and cells to detect novel and rare cell types
Increase your power to identify disease-specific aberrations
With the least hands-on time and lowest cost, get your atlas done with fewer resources

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Biomarker and Drug Discovery

Identify disease-relevant cell types and targets with confidence across more samples
High-throughput drug screening is now possible – capture additional compounds, conditions, timepoints – with a high-definition readout

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Large Patient Cohorts

You don't have to choose favorites– run more of your samples for the greatest statistical power
Streamline processing by fixing and storing samples until you're ready to run
Scale up sample numbers with the confidence of high data quality and reproducibility
Incorporate diverse sample sets to enhance representation across ancestral backgrounds, genders, and age groups

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Longitudinal and Multi-Site Studies

Collect 10s to 100s of samples across different locations and process together without worrying about batch effects
Power your studies by capturing additional timepoints for a more complete picture

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Functional Genomics

Break through the limitations of legacy single cell technology and test 100s to 1,000s of perturbations in a single experiment
Scale your pooled CRISPR screens to identify novel differentiation pathways, drug targets, resistance mechanisms

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Simultaneously process up to hundreds of samples, conditions, or timepoints for ultimate laboratory efficiency

No specialized instruments required

Multiplex samples seamlessly with ScalePlex technology

Trust your results with highly sensitive detection chemistry

Reduce batch effects with simplified sample processing

Achieve cell recovery rates of ≥ 65%

Easily automatable on existing liquid handlers Read app note

Scale up while getting the most from your budget

Capture more samples, timepoints, and conditions for making groundbreaking discoveries. Your budget goes much further with Scale Bio. *Cost includes library prep and sequencing (NovaSeqX 25B flowcell), 5-7k cells per sample.

Scale up while minimizing hands-on time

Scale Bio-generated single cell libraries have similar hands-on time as droplet-based technologies that require specialized instrumentation (n=125,000 cells), and less hands-on time than combinatorial indexing methods.

Scale up while streamlining lab efficiency

Confidently scale sample numbers with minimal impact on library construction time. *Time includes library prep and sample fixation for 1,000 cells per sample. Droplet technology assumes running 8 channels per chip, and hashing assumes 8 samples per channel. Probe-based droplet technology assumes a 16-plex sample pool per channel.

Flexible and easy workflow

Timeline for a 50-sample experiment with 10,000 cells per sample.

Seamless sample multiplexing with ScalePlex

Novel oligo-based ScalePlex technology allows you to run 10s-100s of samples or conditions in a single run without the need for upfront optimization or individual fixation and washing steps. *Multiplexing capacity of commercially available reagents

large-Figures_100M_Cell_Campaign_Automation graph

Easily automate the Scale Bio RNA workflow on existing liquid handlers

Reduce hands-on time to less than 3 hours for 96 samples compared to 4.5 hours or more for other automated workflows. *Click on image above to download automation app note